Infection by HIV , the computer virus that make AIDS , can really be prevented . In the laboratory , the drug tenofovir blocks HIV before it can attack cell . But have the drug to process in the substantial world has been an enormous challenge . Now , researcher have found a method of implementing tenofovir that ’s enormously effective in animal trial , using the familiar intravaginal birth control machine ring .
https://gizmodo.com/a-new-frankenstein-molecule-makes-hiv-cells-self-destru-1350143672
In ordering for tenofovir to block sexually transmit HIV in women , the drug must be present in the vaginal mucosa . However , incorporating the drug in a topical colloidal gel has been ineffectual , in part due to the difficulty of properly clock pane before and after sexual contact . So a team led by Northwestern University Professor Patrick Kiser modernize an intravaginal ring ( IVR ) that deliver a uninterrupted dose of the protective drug . In a small trial on scallywag published last week in Proceedings of the National Academy of Sciences , the drug - administer doughnut was 100 % in force in blocking HIV contagion .
The IVR could solve the major problems that have prevented tenofovir from being effective in the human universe . Unlike gel , which must be precisely timed around intimate encounters to be good , a tenofovir IVR would provide a sustained drug dose over a longer term . Contraceptive IVRs are already in wide use , meaning one less challenge for implementation .
As with any medical advance , these findings must be viewed with restraint . While this first round of animal examination is supporting , we ’re still a long way from a Earth without HIV . The first human safety test , which will measure only how much drug is put out , begin later this year , and we ’re still far away from studying whether tenofovir IVRs can block HIV in homo . But it ’s a promising move toward a reliable and effective pecker to fight HIV transmission in women . [ MedicalXpress ]
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