How science will ruin the drug binge you had planned for this weekend

Rehab is n’t a reliable way of getting off drugs , so neuroscientist are investigating ways to make drugs that will forbid you from pose high in the first place . Now a new discovery promises to make your brain whole immune to the effects of cocain .

Published this week in Nature Neuroscience , the work investigated receptors in your brain that are often targeted by drug like marijuana and cocaine . These “ cannabinoid receptors ” are connected to the brain ’s reward scheme , but we ’re still somewhat unsure of how they work . Now it seems that sure drugs mess with one kind of cannabinoid receptor in an unexpected fashion . Instead of become you eminent , these drug sober up you up . When coke - hook blabber took the drugs , they were much less interested in ego - administering cocain . And they showed fewer effect from the cocaine they take up .

allot to a release about the study :

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Cannabinoids are psychoactive compounds , detect for exercise in marijuana , and their behavioural effects are mediated by the cannabinoid receptors CB1 and CB2 . While drugs that spark off the CB1 sense organ are hump to perk up the brain ’s reward system and provoke relapse to drug seeking after sustain withdrawal , the role of mentality CB2 receptor in modulating the effect of drug - of - abuse is not known .

Zheng - Xiong Xi and colleagues found two classes of drugs that selectively trip the CB2 sense organ . When these drugs were given to computer mouse just before they were allowed to ego - administer cocaine , the team discovered that CB2 activating reduced the bouts and amount of drug intake , as well as the subsequent cocain - bring on locomotor - hasten effects insure in the black eye .

Either Xi and co-worker have find the ultimate drug for crack addict who need to sober up like a shot , or they ’ve direct us one footstep closer to curing destructive drug addictions . Xi ’s team is one of several groups work on drugs that could manipulate cannabinoid sensory receptor to control addiction , so you may be go out “ sombre pill ” on the market sooner than you think .

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